ГЭОТАР-Медиа Clinical genetics. Textbook Бочков Николай Павлович, Пузырев Валерий Павлович, Смирнихина Светлана Анатольевна

Все главы учебника переработаны и дополнены в связи с развитием медицинской науки и практики. Существенно дополнены главы по многофакторным заболеваниям, профилактике, лечению наследственных болезней,экологической генетике и фармакогенетике. Весь теоретический материал проиллюстрирован схемами и рисунками.В учебнике представлены новые, выявленные в последние годы закономерности направлений генетики (эпигенетика, малые РНК, однородительские дисомии, генетический полиморфизм и др.) • В приложении на компакт-диске размещены дополнительные статьи о лечении наследственных болезней, мутагенезе, евгенике.Предназначен студентам медицинских вузов, обучающимся по специальностям "Лечебное дело", "Педиатрия", "Медико-профилактическое дело" подисциплине "Медицинская генетика"

Национальные руководства - первая в России серия практических руководств по основным медицинским специальностям, включающих всю основную информацию, необходимую врачу для непрерывного последипломного образования • Национальное руководство "Наследственные болезни" содержит актуальную, современную информацию о геноме человека, общих вопросах медицинской генетики, клинической генетике. Руководство состоит из двух частей, в которых излагаются теоретические и клинические вопросы медицинской генетики • В первой части представлены новейшие данные по теоретическим вопросам медицинской генетики. Сведения об организации и функциях генома, генов и хромосом изложены в понятной для врачей форме, но без излишнего упрощения • Во второй части представлены вопросы клинической генетики, а именно методы диагностики наследственных болезней (от клинического уровня до секвенирования ДНК и РНК), принципов лечения и профилактики отдельных нозологических форм

Краткое издание национального руководства «Наследственные болезни» отличается от полного издания не только объемом, но и структурой • Оно практически не содержит базовых понятий медицинской генетики, таких как геном человека, хромосомы и гены человека и т.д., но зато в нем усилена прикладная направленность • В книге описаны основные типы наследственных болезней, начиная с моногенных и заканчивая многофакторными и тератогенно обусловленными, представлены основные принципы лабораторной диагностики наследственных болезней обмена веществ и других классов наследственных болезней, а также пренатальной и предимплантационной генетической диагностики. Освещены вопросы лечения наследственных болезней, генной терапии, медико-генетического консультирования, неонатального скрининга, социальной значимости груза наследственных болезней и этических проблем медицинской генетики

This textbook is composed in accordance with the requirements of the current Federal State Educational Standards of Higher Education for the spe ciality 31.05.01 “General Medicine” and with the training program for the subject “Outpatient Therapy”. The textbook is organized according to the module principle and contains summary of fundamental knowledge of diagnosis, treatment, prevention of chronic non-communicable diseases as well as regular medical outpatients check-up • The theoretical material is systematized, corresponds to state-of-the art achievements of science and clinical practice in the fi eld of internal medicine, accompanied by self-control questions and references to current literature for independent study • The textbook is designed for undergraduate and postgraduate English speaking students studying this subject in Russian universities

The textbook addresses the issues of rehabilitation of patients with diseases of the cardiovascular, respiratory, central and peripheral nervous systems, digestive system, with di seases and injuries of the musculoskeletal system, metabolic disturbances, infectious diseases, including tuberculosis, as well as the issues of application of rehabilitation technologies in obstetrics and gynecology. Regulatory environment, clinical medical substantiation of using the methods and facilities of medical rehabilitation are represented in this textbook, as well as basics of medical and social rehabilitation of the physically impaired. Specific features of medical supervision and nutritional support in medical rehabilitation are disclosed. Composition of rehabilitation programs is described in view of the administration of the motive regimen, remedial gymnastics, massage, physiotherapeutic procedures, reflexotherapy, psychotherapy, and sensible nutrition

Presented by the team of leading Russian experts in various branches of internal medicine under Academician Anatoly Martynov, this edition of the textbook contains most current information on basic therapeutic diseases. The book provides updated information on etiology, pathogenesis, diagnosis, treatment and prevention of internal organs diseases. Traditional presentation of the material is based on actual recommendations of professional medical communities and most recent scientific findings • The edition corresponds to the academic program on such disciplines as Intermediate Level Therapy and Hospital Therapy and is intended for senior students of medical schools, students specialized in General Medicine, Pediatrics, Medical and Preventive Care, Medical Biophysics, Medical Biochemistry and for clinical residents specialized in Therapy

Presented by the team of leading Russian experts in various branches of internal medicine under Academician Anatoly Martynov, this edition of the textbook contains most current information on basic therapeutic diseases. The book provides updated information on etiology, pathogenesis, diagnosis, treatment and prevention of internal organs diseases. Traditional presentation of the material is based on actual recommendations of professional medical communities and most recent scientific findings • The edition corresponds to the academic program on such disciplines as Intermediate Level Therapy and Hospital Therapy and is intended for senior students of medical schools, students specialized in General Medicine, Pediatrics, Medical and Preventive Care, Medical Biophysics, Medical Biochemistry and for clinical residents specialized in Therapy

This textbook is a contribution by a community of experienced lecturers from the Academician A.I. Strukov Department of Pathological Anatomy, I.M. Sechenov First Moscow State Medical University (Sechenov University), among contributors there are also leading experts from other medical universities. Coverage of the main issues of general and special pathological ana tomy is based on the principle of unity between structure and function. The authors tried to show not only the morphological basis of pathological processes and diseases, but also their connection with changes in body functions, resulting in certain symptoms of diseases, as well as the dynamics of their development. This approach provides a basis for further study of all clinical disciplines

The textbook for students, studying the basic course of pathophysiology in English, is organized according to the module principle and contains summary of lectures on the specific module’s topic, tests, clinico-pathophysiological and clinico-laboratory cases for training and control of knowledge, algorithms of solution of the typical problems, and also questions to prepare for classes, colloquia and final examination on pathophysiology • The edition contains the discussions of the subject matter of pathophysiology; its aims, issues, methods, and constituent parts. It summarizes the main concepts of general nosology, etiology and pathogenesis. In a concise format or in a form of schemes, it considers the causes, mechanisms of development, adaptive reactions, manifestations and outcome of the typical pathologic processes and typical forms of pathology of organs and physiological systems, including separate syndromes and nosologic units

The textbook deals with general issues of surgery (aseptics and antiseptics, haemorrhage, and principle blood transfusion, fundamentals of resuscitation and pain treatment, specifi cs of work-up surgical patient, and surgical operation); the textbook elucidates the pathological processes underlying surgical diseases (traumas, pyoinfl ammatory diseases, tumors, parasitogenic surgical diseases, and maldevelopments requiring surgical treatment). Each chapter is complemented with control questions and tasks • The textbook is intended for students and teachers at medical higher educational institutions. It will be also useful for junior surgeons, medical residents, postgraduates and doctors

The textbook outlines the main provisions of forensic medicine in accordance with the syllabus for the course of Forensic medicine at higher professional education establishments, and an innovative modular educational program. The textbook captures the current achievements of forensic medicine in areas of forensic traumatology, tanatology and person’s identification. All information is presented in the form of a system of interconnected modules, with consideration to the Bologna Declaration, latest updates in legislation and new regulations on determining the severity of harm to human health • The textbook can provide invaluable assistance to students in obtaining theoretical knowledge and mastering practical skills for further work in the field of forensic medicine

The textbook corresponds to the curriculum of the Mathematics discipline in pharmaceutical and medical higher educational institutions, based on the Federal State Educational Standard for Higher Professional Education of the Third Generation • The textbook presents a course of mathematics that includes basic elementary functions, diff erential calculus of functions of one variable, elements of diff erential calculus of multiple variable functions, integral calculus of one variable functions, diff erential equations of the fi rst and second order, fundamentals of probability theory and mathematical statistics • In the textbook, there are detailed explanations of theoretical material and a large number of examples and issues fully explained • It is intended for undergraduate and postgraduate students of medical and pharmaceutical universities, doctors, pharmacists and individuals, who study mathematics and mathematical statistics by themselves